Liver transplantation and primary biliary cirrhosis.
نویسندگان
چکیده
منابع مشابه
Primary biliary cirrhosis and liver transplantation.
Primary biliary cirrhosis (PBC) is an immune-mediated chronic progressive inflammatory liver disease, predominantly affecting middle-aged women, characterized by the presence of antimitochondrial antibodies (AMAs), which can lead to liver failure. Genetic contributions, environmental factors including chemical and infectious xenobiotics, autoimmunity and loss of tolerance have been aggressively...
متن کاملLiver transplantation in primary biliary cirrhosis.
The proportion of patients who undergo liver transplantation for primary biliary cirrhosis (PBC) is steadily declining. This decline is partly from the increasing number of patients undergoing transplantation for other indications, but also perhaps because of the effect of ursodeoxycholic acid (UDCA) on the natural history of this condition. Nevertheless, patients who have PBC still constitute ...
متن کاملLiver transplantation for primary biliary cirrhosis.
Liver transplantation is the accepted treatment for patients with end-stage liver disease or intractable symptoms secondary to primary biliary cirrhosis (PBC), and has proven survival benefit. Indications for transplantation are an unacceptable quality of life or anticipated death in less than 1 year. Although there are a number of prognostic models, serum bilirubin provides the simplest guide ...
متن کاملDifficult Decisions Liver transplantation and primary biliary cirrhosis
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease, autoimmune in 'nature', but ofunknown aetiology." 2 It often presents in middle-aged women with itching, jaundice, hepatomegaly or variceal bleeding.3 Increasingly the diagnosis is made in asymptomatic patients or those without symptoms referrable to the liver,4 often in association with other autoimmune diseases, on the ba...
متن کاملLate-onset sarcoidosis after liver transplantation for primary biliary cirrhosis.
Primary biliary cirrhosis (PBC) and systemic sarcoidosis are granulomatous diseases of unknown etiology whose hepatic manifestations may infrequently be imitative of one another. Described herein is the first reported case in the medical literature of systemic sarcoidosis developing after liver transplantation for PBC. The presented patient, who suffered from typical clinical, laboratory, and p...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1989
ISSN: 0032-5473
DOI: 10.1136/pgmj.65.766.553